Ankylosing spondylitis is a form of arthritis that affects spine. It is an autoimmune disease. Inflammation of spine and sacroiliac joints is chronic. Inflammation can lead to severe, chronic pain and discomfort. It can also cause inflammation, pain and stiffness in shoulders, hip, ribs, heels and small joints of hand and feet. It can also cause Overtime chronic inflammation of spine leads to the fusion of vertebrae and patient is not able to move spine. Men are more prone to this disease rather than women.